Psuedoangiomatous Squamous Cell Carcinoma In The Oral Cavity Of A Dog
By : Tim Cushing, Sandra Barnard, Rebekah Fleis, Rachel Peters
An 8-year-old, spayed, female Labrador Retriever mixed-breed dog was presented to the Cornell University Hospital for Animals with an invasive oral mass involving the upper left fourth premolar and first molar teeth. Initial biopsy results suggested a poorly differentiated squamous cell carcinoma, whereas further histologic examination of the surgically removed mass revealed a hemangiosarcoma-like mass composed of numerous vascular clefts and variable numbers of keratinizing epithelial cells. Hist logic and immunohistochemical characteristics were compatible with pseudoangiomatous squamous cell carcinoma, a well recognized human variant of acanthomatous squamous cell carcinoma. Because of histomorphologic similarities with canine gingival hemangiosarcoma, diagnosticians should be aware of the present tumor variant as a differential diagnosis for vascular-like growths in the oral cavity of dogs.
Preclinical Evaluation Of The Novel, Orally Bioavailable Selective Inhibitor Of Nuclear Export (SINE) KPT-335 In Spontaneous Canine Cancer
By : Cheryl A. London, Luis Feo Bernabe, Sandra Barnard, William C. Kisseberth, Antonella Borgatti, Mike Henson, Heather Wilson, Kiersten Jensen, Daisuke Ito, Jaime F.
By : Daniel R James, David Collins, Philippa J Johnson and Andrew M Marchevsky Case Summary A 10-month-old female spayed domestic shorthair cat was presented
Maintenance Therapy With Toceranib Following Doxorubicin Based Chemotherapy For Canine Splenic Hemangiosarcoma
By : Heather L. Gardner, Cheryl A. London, Roberta A. Portela, Sandra Nguyen, Mona P. Rosenberg, Mary K. Klein, Craig Clifford, Douglas H. Thamm, David
Evaluation Of The Adverse Event Profile And Pharmacodynamics of Toceranib Phosphate Administered To Dogs
By : Luis Feo Bernabe, Roberta Portela, Sandra Nguyen, William C Kisseberth, Michael Pennell, Mark F Yancey and Cheryl A London Background The receptor kinase
By : Sanaa Zaki, S. Tzannes, M. Govendir, Richard Malik The ferret has unique anatomical and physiological characteristics, which favour the use of inhalational agents